BIOCHEMISTRY

About this course

Biochemistry is the branch of science concerned with studying the chemical processes and substances that occur within living organisms.

Biochemistry and medicine enjoy a mutually cooperative relationship. The many functions that human organs perform are oftentimes based on chemical processes. One cannot hope to master the comprehension of Physiology without a solid grasp of Biochemistry, the basis of all metabolic processes.

The substances and reactions that are the subjects of the study of Biochemistry are also important players in the understanding of cellular biology, microbiology or the effects organisms can have on the human body, and the pharmacologic effects of medications.

2Biochemistry

Content

Speaker

Kevin Ahern, PhD

Dr. Kevin Ahern is a Professor in the Department of Biochemistry and Biophysics at Oregon State University (OSU), USA.
He obtained his PhD in Biochemistry from Oregon State University. Currently, he teaches courses for health sciences students at OSU.
He is co-author of three Open Educational electronic textbooks on Biochemistry and a Guide to Getting Into Medical School.
Due to his achievements, he earned OSU’s highest teaching recognition, the Elizabeth P. Ritchie Distinguished Professor Award in 2017.

Video lectures

01. Enzymes and Enzyme Kinetics

  • Enzymes and Enzyme Kinetics Enzyme Catalysis
  • Enzymes and Enzyme Kinetics Enzyme Classification
  • Enzymes and Enzyme Kinetics Reversible & Irreversible Enzyme Inhibitors

02. Amino Acid Metabolism

  • Amino Acid Metabolism Introduction
  • Proline and Arginine Synthesis
  • Serine Family and Methionine Catabolism
  • Cysteine Metabolism
  • Aspartate Family and Asparagine Metabolism
  • Methionine, Threonine and Lysine Metabolism
  • Aromatic Family Tryptophan
  • Aromatic Family Phenylalanine and Tyrosine
  • Tyrosine Precursor of Thyroid Hormones
  • Pyruvate Family Alanine Metabolism
  • Leucine (LEU), Valine (VAL), Isoleucine (ILE) and Histidine (HIS) Metabolism
  • Amino Acid Catabolism
  • Nitrogen, Nitrogen Cycle and Excretion of Nitrogen
  • Glutamate Central Role
  • Urea Cycle
  • Carbamoyl Phosphate Synthetase Reaction and Citrulline
  • Argininosuccinate Synthetase
  • Urea Cycle and Disease
  • Nitrites and Nitrosamines
  • Reactive Nitrogen Species
  • Heme Introduction
  • Heme Synthesis
  • Porphyrias
  • Iron Transport and Storage
  • Regulation of Iron Transport
  • Hemoglobin and Movement of Oxygen Introduction
  • Cooperativity
  • Bohr Effect
  • 2,3 BPG
  • Movement of CO2
  • Fetal Hemoglobin
  • Sickle Cell Anemia
  • Biochemistry of Bilirubin
  • Biochemistry of Bilirubin Biliverdin Reductase
  • Enterohepatic Circulation and Health

03. Vitamins

  • Vitamin A Introduction
  • Vitamin A Steps in Light Detection
  • Vitamin A Color Detection, Visual Cycle and Retinoic Acid
  • 01.04 Vitamin D Introduction
  • Vitamin D3 and Calcium
  • Vitamin D and Calcium Levels
  • Vitamin D and Intracellular Actions
  • Vitamin K
  • Vitamin E
  • Vitamin B12
  • Folate Metabolism and Recycling
  • Folate Metabolism Overview and Health

04. Hormones and Signal Transduction

  • Hormones and Signal Transduction Introduction
  • Receptors and Messengersion
  • Protein Coupled Receptors (GPCRs)
  • Actions of the Second Messenger and Protein Kinase A
  • Receptor Tyrosine Kinase Signaling
  • Epidermal Growth Factor Receptor (EGFR)
  • Nuclear Hormone Receptors and Steroid Hormone Signaling
  • Non-Hormone Signaling and Nerve Transmission
  • Signaling Gone Wild
  • HER2 Receptor and Bcr-Abl

05. RNA and the Genetic Code

  • RNA Basic Knowledge
  • Complexity of RNA Structure
  • RNA & Genetic Code
  • Collagen Background
  • Biochemistry of Collagen
  • Clinical Biochemistry

06. Carbohydrate Metabolism

  • Carbohydrate Metabolism Glycolysis & Pyruvate Metabolism
  • Carbohydrate Metabolism Gluconeogenesis
  • Carbohydrate Metabolism Glycogen Metabolism
  • The Pentose Phosphate Pathway Introduction

07. Analytical Techniques in Biotechnology

  • Biotechnology Analytical Techniques

08. DNA Replication and Repair

  • DNA Replication & DNA Repair

09. Metabolic Control

  • Metabolic Control of Enzyme Activity
  • Metabolic Control Advanced

10. Lipid Metabolism

  • Lipid Metabolism Fat & Fatty Acids
  • Lipid Metabolism Steroids & Bile Acids
  • Membrane Lipid Metabolism

11. Purine and Pyrimidine Metabolism

  • Nucleotide Metabolism Introduction and De novo Purine Metabolism
  • Paths to Guanine and Adenine Nucleotides
  • Purine de novo Metabolism Regulation
  • Pyrmidine de novo Metabolism ATCase Reaction
  • Pyrmidine de novo Metabolis OMP Decarboxylase and Synthesis of UTP & CTP
  • Catabolism of Guanine Nucleotides and Adenine Nucleotides
  • Catabolism of Guanine & Hypoxanthie and Purine Nucleotide Salvage
  • Pyrimidine Catabolism and Salvage Reactions
  • Deoxyribonucleotide Synthesis and Ribonucleotide Reductase
  • Nucleotide Metabolism and Thymidine Metabolism
  • Thymidylate Synthase and Recycling of Folates
  • Nucleoside Analogs and Deoxyadenosine Analogs
  • Analogs Adenosine, Deoxycytidine, GuanosineDeoxyguanosine, Thymidine, Deoxyuridine